Tommaso Percivale Ribelli In Fuga Pdf 49
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Knowledge concerning the way in which muscle fibers are organized in muscle and tendon has expanded greatly during recent years. The histological picture presented by nerve, muscle, tendon, and blood vessels from the point of view of subcellular organelles is in most instances quite clear, but what is missing most is knowledge of the way in which these structures are arranged and intertwined in muscle and tendon. New studies from scanning and transmission electron microscopy are helping to fill this gap. Light microscopy gives information about the organization of the connective tissue fibers, but is lacking in resolving the important question of how the muscle fibers are anchored to the tendon or connective tissue, and how they are related to each other. New freeze-fracture and freeze-etch studies now show that the linkages of muscle fiber to tendon, that is, the z-bands, are multi-layered, multilamellar, and bilayered. In the case of the tendon, the outer limit of the z-bands is covalently bound, but in the case of the muscle, the outer limit is only protein-associated. Freeze-etch analysis also reveals that in muscle fibers the A-bands contain mostly actin filaments with a little protein. Since A-bands are the first point of contact of a muscle fiber to the connective tissue, it is suggested that this observation may indicate that the only part of the muscle fiber to reach the
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